Sabres vs. Bruins Prediction & Picks - March 25

The Buffalo Sabres (44-20-7) take on the Boston Bruins (39-24-8) at KeyBank Center on Wednesday, March 25 at 7:30 p.m. ET on TNT, with both teams back in action after a loss. The Sabres fell to the Anaheim Ducks 6-5 in overtime in their most recent game, while the Bruins are coming off a 4-2 loss to the Toronto Maple Leafs.

Watch the NHL, other live sports and more on HBO Max. Use our link to sign up today.

Prepare for this showdown with a look at who we predict will come out on top in Wednesday's game.

During the past 10 games for the Bruins, their offense has put up 30 goals while their defense has given up 26 (they have a 5-2-3 record in those games). In 35 power-play opportunities during that span, they have scored five goals (14.3% conversion rate).

Sabres vs. Bruins Predictions for Wednesday

Our computer projections model for this game predicts a final tally of Sabres 4, Bruins 3.

• Moneyline Pick: Sabres (-207)
• Total Pick: No Pick - Predicted Margin Negligible
• Spread Pick: Bruins (+1.5)

Catch NHL action all season long on HBO Max.

Sabres Splits and Trends

• The Sabres (44-20-7 overall) have a 7-7-14 record in matchups that have gone to overtime.
• Buffalo is 9-3-7 (25 points) in its 19 games decided by one goal.
• In the seven games this season the Sabres scored just one goal, they finished 0-6-1.
• Buffalo has taken 10 points from the 12 games this season when it scored a pair of goals (5-7-0 record).
• The Sabres are 39-4-6 in the 49 games when they have scored three or more goals (to register 84 points).
• In the 26 games when Buffalo has recorded a lone power-play goal, it has a 17-5-4 record (38 points).
• In the 27 games when it outshot its opponent, Buffalo is 16-9-2 (34 points).
• The Sabres have been outshot by opponents in 44 games, going 28-11-5 to record 61 points.

Bruins Splits and Trends

• The Bruins (39-24-8 overall) have posted a record of 10-8-18 in games that have needed OT this season.
• Boston has earned 33 points (14-6-5) in its 25 games that finished with a one-goal margin.
• This season the Bruins scored just one goal in eight games and have gone 1-6-1 (three points).
• Boston has earned 13 points (6-9-1 record) this season when scoring exactly two goals .
• The Bruins have scored three or more goals 47 times, earning 70 points from those matchups (32-9-6).
• This season, Boston has recorded a single power-play goal in 33 games has a record of 16-12-5 in those matchups.
• When outshooting its opponent this season, Boston is 13-10-3 (29 points).
• The Bruins' opponents have had more shots in 43 games. The Bruins finished 26-12-5 in those matchups (57 points).

Looking for NHL tickets? Head to StubHub today and see your team live.

Team Stats Comparison

Sabres vs. Bruins Game Time and TV Channel

• When: Wednesday, March 25, 2026 at 7:30 p.m. ET
• TV Channel: TNT
• Live Stream: Watch this match on HBO Max (Regional restrictions may apply)
• Where: KeyBank Center in Buffalo, New York

Sign up for HBO Max to watch the Sabres play Bruins.